Ku ya 31 Werurwe 2026, Ikigo gishinzwe gusuzuma imiti mu Bushinwa gishinzwe ubuvuzi cyatanze inkuru ishimishije: GFH375, yakozwe na GenFleet Therapeutics, yashyizwe ku mugaragaro nk'umuti uvura indwara zikomoka ku ruhu (“Breakthrough Therapy”) mu kuvura abarwayi barwaye kanseri ya pancreas ifite imiterere ya KRAS G12D mutation, bakaba barahawe nibura ubuvuzi bumwe mbere. Ibi bigaragaza intambwe ikomeye mu rwego rwo kuvura kanseri ya pancreas neza.
Niba wowe cyangwa uwo ukunda arwaye kanseri ya pancreas ya KRAS G12D ikomeje kugaragara, ntucike intege. Ishami Mpuzamahanga ry’Ibitaro bya Oncology bya Beijing mu Karere k’Amajyepfo (400-880-3716) riri gukurikirana neza iyi gahunda igezweho kandi ritanga serivisi z’ubujyanama n’ubujyanama ku barwayi mpuzamahanga.
**Ibyerekeye GFH375/VS-7375**
GFH375 ni umuti ugabanya ubukana bw’uturemangingo duto twa KRAS G12D (ON/OFF) mu kanwa, ukomeye kandi utoranya cyane, wagenewe kwibasira ihererekanya rya GTP/GDP, bityo ugahagarika uburyo bwo kwinjira mu nzira yo hasi no kugabanya ku buryo bufatika ikwirakwira ry’uturemangingo twa kanseri. Inyigo zakozwe mbere y’isuzuma ryerekanye ko ingano y’uturemangingo iterwa n’umuti iterwa n’umuti mu buryo busanzwe, mu buryo bugaragaza impinduka za KRAS G12D; GFH375 kandi yagaragaje ko hari ingaruka nke mu guhitamo neza no gusuzuma ingamba z’umutekano.
GenFleet yagiranye ubufatanye mu kuvumbura no guteza imbere Verastem Oncology (Nasdaq: VSTM) kugira ngo iteze imbere gahunda eshatu nshya za kanseri zigamije kanseri zishingiye kuri RAS/MAPK. Ubu bufatanye buha Verastem amahitamo yihariye yo kubona uruhushya kuri buri kimwe muri ibyo bintu bitatu nyuma yo kurangiza neza intambwe zagenwe mu igerageza rya Phase I. Mu Kuboza 2023, Verastem yahisemo GFH375/VS-7375, umuti ubuza KRAS G12D (ON/OFF) wo mu kanwa, nk'ingamba yayo y'ibanze iturutse ku bufatanye, kandi uruhushya rwa GFH375 rwakoreshejwe muri Mutarama 2025 rwari urwa mbere muri ubu bufatanye. Izi mpushya ziha Verastem uburenganzira bwo guteza imbere no gucuruza hanze y'Ubushinwa, mu gihe GenFleet igumana uburenganzira mu Bushinwa.
**Amakuru y'igerageza ry'ubuvuzi ry'icyiciro cya mbere/icya kabiri ashimishije yatanzwe mu nama ya ESMO yo mu 2025:**
- 91.5% by'abarwayi bagabanutse ibikomere by'inzobere
- Igipimo cy'igisubizo cy'intego (ORR) cyageze kuri 40.7%
- Igipimo cyo kurwanya indwara (DCR) cyari hejuru cyane kigera kuri 96.7%
- Kurokoka hagati y’igihe nta ntambwe (mPFS) byari amezi 5.52
- Igipimo cyo kubaho kidashingiye ku iterambere ry'amezi 4 cyari 78.2%
Aya makuru, yavuye ku barwayi 59 bafite KRAS G12D-mutant pancreatic ductal adenocarcinoma (PDAC) yateye imbere bari barahawe ubuvuzi bw’umubiri mbere, agaragaza neza ko GFH375 irwanya kanseri ya pancreatic idashobora kugaragara.
**Kuki wahitamo Ishami Mpuzamahanga ry’Ibitaro bya Oncology byo mu Karere k’Amajyepfo ka Beijing?**
Nk’umutambyi mukuru mu buvuzi mpuzamahanga, Ishami Mpuzamahanga ry’Ibitaro bya Oncology bya Beijing mu Karere k’Amajyepfo ryiyemeje guha abarwayi bo ku isi yose ibi bikurikira:
- Serivisi zo kugisha inama abaganga b'inzobere mu ndimi nyinshi no kubonana na bo
- Kubona impuguke zikomeye mu bijyanye na kanseri haba mu Bushinwa no ku rwego mpuzamahanga.
- Umuyoboro umwe w’icyatsi kibisi wo kuvurirwamo abaganga bambukiranya imipaka
Tuzi neza ko ku barwayi ba kanseri ikomeye, buri munsi wo gutegereza wiyongereyeho uzana ibyago byinshi. Kubwibyo, twashyizeho inzira nyinshi zo kuvugisha mpuzamahanga kugira ngo tumenye neza ko ubona ubufasha bw'abahanga ku gihe.
**Twandikire uyu munsi utangire urugendo rwawe rw'ibyiringiro**
���� Umurongo w'itumanaho: 400-880-3716
���� WeChat: 17801183037
���� Imeri:
- 100085_010@163.com
- myimmnet@163.com
Uko igihugu cyangwa akarere waba urimo kose, cyangwa uburyo bwinshi bwo kuvura wagerageje, Ishami Mpuzamahanga ry’Ibitaro Mpuzamahanga bya Oncology bya Beijing Region South ririteguye kugufasha mu rugamba rwawe rwo kurwanya kanseri. Intambwe ya GFH375 ishobora kuba urumuri wari utegereje.
Call 400-880-3716, add us on WeChat at 17801183037, or email us at 100085_010@163.com or myimmnet@163.com.
Twese hamwe, nimuze duharanire amahirwe menshi yo kubaho.
> Icyitonderwa: GFH375 ntirahabwa uburenganzira bwo kugurishwa ku mugaragaro mu Bushinwa. Biteganijwe ko ubuvuzi bwayo bugezweho buzihutisha uburyo bwo kuvura. Ishami Mpuzamahanga ry’Ibitaro bya Oncology bya Beijing mu Karere k’Amajyepfo rizakurikirana hafi iterambere ry’imiti kandi ritange amakuru ku buryo bugezweho bwo kuvura no guhuza abarwayi bujuje ibisabwa. Nyamuneka kurikiza amabwiriza ya muganga wawe ku bijyanye na gahunda zihariye zo kuvura.
Igihe cyo kohereza: 10 Mata 2026