Ku ya 31 Nyakanga 2025, ikigo ImmuneOnco Biopharmaceuticals cyatangaje amakuru y’ibanze ku mutekano n’ubushobozi bw’imiti yavuye mu bushakashatsi bwakozwe ku cyiciro cya kabiri bwakozwe ku ishami rishinzwe imiti ya IMM2510 hamwe na chimiotherapie ku barwayi barwaye kanseri y’ibihaha itari iy’uturemangingo duto (NSCLC) bwakorewe mu Bushinwa.
Ku ya 1 Nyakanga 2025, abarwayi 33 bahawe 10 mg/kg, abarwayi 21 bakaba barapimwe nibura kimwe cya kanseri (isuzuma ry’imikorere y’imiti). Ibisubizo by’igice byagaragaye muri 62% by’abarwayi bapimwe ingaruka z’imiti, birimo 80% (8/10) by’abarwayi bafite squamous NSCLC na 46% (5/11) by’abarwayi bafite squamous NSCLC. Abenshi mu barwayi bapimwe ingaruka z’imiti bakoze isuzuma rimwe gusa ku gihe cy’isesengura ry’imiti. ImmuneOnco yiteze gutanga amakuru y’umutekano n’imikorere y’imiti mu igerageza rya IMM2510 rihuza imiti ya chimiotherapie mu nama y’ubuganga iteganyijwe mu gihe kizaza.
Imiterere y’umutekano wa IMM2510 ishyigikira iterambere ry’ubuvuzi, nta burozi bugabanya urugero rw’umuti bwagaragaye ku barwayi 33 bapimwe ku mutekano. Muri aba barwayi, nta ngaruka mbi zijyanye n’ubuvuzi (TRAE) zatumye dose igabanuka cyangwa igapfa, kandi TRAE imwe gusa ni yo yatumye imiti ihagarara. TRAE zo mu cyiciro cya 3+ zikunze kugaragara zari iz’amaraso, hamwe n’izindi ngaruka zidasanzwe. Ingaruka mbi zikunze kugaragara zijyanye no gukumira VEGF (urugero: umuvuduko ukabije w’amaraso, poroteyine, hemoptysis) n’ingaruka mbi zijyanye n’ubudahangarwa bw’umubiri ntabwo zari zisanzwe kandi muri rusange zari nke, kandi ingaruka zijyanye no guterwa infusion hafi ya zose zari nke.
Kugeza ubu, haracyari igeragezwa ryinshi ry’ikoranabuhanga rishya rirwanya kanseri mu Bushinwa rishaka abarwayi. Inama ku miti mishya n’ikoranabuhanga, ushobora kuvugana n’Ishami Mpuzamahanga ry’Ibitaro bya Oncology bya Beijing mu Karere k’Amajyepfo.
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Igihe cyo kohereza: Kanama-05-2025