Bwana X ni umurwayi uri mu kigero cy'imyaka 40 wafashwe na acral melanoma. Nyuma yo kubagwa bikomeye nyuma yo kuvurwa mu 2015, yakomeje kugira ubuzima bwiza mu gihe cy'imyaka icyenda. Ikibabaje ni uko hashize umwaka umwe, indwara ye yongeye kugaruka hamwe na metastases mu bihaha byombi. Nubwo yaciwe inguinal na pelvic lymph node ndetse no kuvurwa mu buryo bwa gatatu (harimo kuvurwa antibody ya PD-1 na NRAS mutation-target therapy), ibibyimba byagiye bibangamira cyane ibihaha byombi, mu kibuno, mu nda, mu rukuta rw'iburyo rw'inda, ndetse no mu mitsi yo mu mugongo, bigatera ububabare bukomeye no kugabanuka gukomeye kw'ubuzima.
Kugeza ubu, haracyari igeragezwa ryinshi ry’ikoranabuhanga rishya rirwanya kanseri mu Bushinwa rishaka abarwayi. Inama ku miti mishya n’ikoranabuhanga, ushobora kuvugana n’Ishami Mpuzamahanga ry’Ibitaro bya Oncology bya Beijing mu Karere k’Amajyepfo.
Nimero ya Terefone: 4008803716
Indangamuntu ya WeChat: 17801183037
Email：myimmnet@163.com
Mu ntangiriro za 2025, Bwana X yitabiriye igerageza rya TIL cell therapy (GC101) maze arangiza guterwa TIL cell infusion mu ntangiriro za Kamena. Nubwo umutwaro we wa kanseri wari munini, aho igisebe kinini cyanganaga na mm 62, ibyumweru bitandatu nyuma yo guterwa, ibisebe bye byose byagabanutseho 31.9%, aho igisebe kimwe kinini cyagabanutseho hafi 40%. Ubushobozi bwo kuvura muri rusange bwageze ku gisubizo cy'igice (PR). Ikirenzeho, Bwana X nta ngaruka mbi zikomeye yagize nyuma yo guterwa GC101 TIL, ahubwo yahuye n'ingaruka mbi zisanzwe zijyanye na immunotherapy nka nko gukonja no kugira umuriro, byahise bikemuka vuba iyo habayeho kuvurwa ibimenyetso.
Ibyerekeye GC101
GC101 ni uburyo bwo kuvura bwa TIL TIL karemano bwakozwe hifashishijwe urubuga rwo kwagura uturemangingo twa Juncell Therapeutics rwa DeepTIL®. DeepTIL® ituma TILs zikora neza ku buryo nta IL-2 ikenewe nyuma yo kuyitera, kandi imbaraga zo kuyivura mbere zishobora kuba nke.
Nk’ubuvuzi bwa mbere bwa TIL bukenera gusa ubuvuzi buke mbere yo kuvurwa kandi nta ntera ya IL-2 ku isi, GC101 yemejwe kubera imikorere yayo mu buvuzi n’umutekano wayo, ibyo bikaba byongera cyane umutekano no kugera ku bushobozi bwo kuvurwa na TIL.
Ku bijyanye na Melanoma
Mu Bushinwa, igipimo cy'impfu za melanoma kiri hejuru kandi igipimo cy'ubwiyongere bw'indwara kigenda cyiyongera uko umwaka utashye. Ugereranyije n'Abanyaburayi cyangwa Abanyamerika, hari itandukaniro rinini mu miterere ya melanoma mu Bushinwa: hafi 90% bya melanoma bituruka ku ruhu mu Banyaburayi n'Abanyamerika. Mu Banyaziya, hafi 50% bya melanoma bituruka ku ruhu na 20-30% mu ruhu. Ibinyuranye n'ibyo, melanoma yo mu ruhu no mu bwoko bwa mucosal ifite imiterere mibi kurushaho.
Kugeza ubu, haracyari igeragezwa ryinshi ry’ikoranabuhanga rishya rirwanya kanseri mu Bushinwa rishaka abarwayi. Inama ku miti mishya n’ikoranabuhanga, ushobora kuvugana n’Ishami Mpuzamahanga ry’Ibitaro bya Oncology bya Beijing mu Karere k’Amajyepfo.
Nimero ya Terefone: 4008803716
Indangamuntu ya WeChat: 17801183037
Email：myimmnet@163.com
Igihe cyo kohereza: Kanama-07-2025